Microbial Fabricated Nanosystems: Applications in Drug Delivery and Targeting

Nanosystems for drug delivery

Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey Abstract Introduction Over the last couple of decades, the area of drug delivery has become important for its possible gaining in the pharmaceutical industry. Studies show that drug delivery systems which are developed by nanotechnology offer the opportunity to achieve more efficient drugs and to ...

Magnetic drug delivery and targeting: principles and applications.

BACKGROUND Nanomaterials are at the leading edge of the rapidly developing field of nanotechnology. Magnetic nanoparticles for cancer therapy and diagnosis have been developed on the basis of their unique physico-chemical properties not present in other materials. Their versatility is widely exploited in such diverse techniques as cell and macromolecule separation and purification, immunoassays...

Bacterial membrane vesicles as novel nanosystems for drug delivery

Bacterial membrane vesicles (BMVs) are closed spherical nanostructures that are shed naturally and ubiquitously by most bacterial species both in vivo and in vitro. Researchers have elucidated their roles in long-distance transport of a wide array of cargoes, such as proteins, toxins, antigens, virulence factors, microbicidal agents and antibiotics. Given that these natural carriers are importa...

drug delivery and targeting in traditional iranian pharmacy

Rational modifications of cell-penetrating peptides for drug delivery Applications in tumor targeting and oligonucleotide delivery

High molecular weight biomolecules are becoming increasingly important in the development of new therapeutics. However, the hydrophilic nature and size of such molecules creates a major limitation for their application – poor penetration through biological membranes. Over a decade ago, a new class of peptides, cell-penetrating peptides (CPPs), with membrane translocating ability, was discovered...